The gut microbiome in livestock is the collection of micro-organisms, including bacteria, fungi, viruses and protozoa, that inhabit the intestinal wall and intestinal contents. This ecosystem plays a key role in digestion, immunity and the overall health of the animal. The questions below map out the most important aspects of the gut microbiome, from composition to the practical implications for production performance.
Which micro-organisms live in the gut of livestock?
The gut of livestock is home primarily to bacteria, but yeasts, fungi, viruses and protozoa are also part of the gut microbiome. The bacterial community is by far the largest and most studied group. In poultry, pigs and ruminants, a mix of bacterial species dominates, together forming a dynamic and functional ecosystem.
In pigs and poultry, the most common bacterial strains come from the phyla Firmicutes and Bacteroidetes. Species such as Lactobacillus, Bifidobacterium and Faecalibacterium are considered beneficial residents that contribute to a healthy gut environment. On the other hand, pathogens such as Escherichia coli, Salmonella and Clostridium can disrupt the balance when conditions allow.
In ruminants such as cattle and sheep, the rumen plays an additional role: here, specialised micro-organisms break down cellulose and other fibres into usable energy sources. The diversity and composition of this microbiota therefore differ greatly between animal species, age and dietary pattern.
How does the gut microbiome develop in young animals?
The gut microbiome in young animals develops extremely rapidly in the first weeks of life. At birth, the gut is virtually sterile; colonisation begins immediately after contact with the environment, the mother and feed. The composition during this early phase is decisive for the health and resilience of the animal in the long term.
In piglets, microbiome formation begins during passage through the birth canal and via sow’s milk. Mother’s milk contains not only nutrients, but also micro-organisms and prebiotic compounds that stimulate the growth of beneficial bacteria. In chicks, this process is different: the chick hatches from the egg without direct transfer from the mother and is therefore strongly dependent on the environment and feed for initial colonisation.
In the first weeks, the microbiome is still unstable and susceptible to disturbances. After weaning in pigs or the transition to solid feed in poultry, a critical period follows in which the microbiota adapts to new nutritional sources. A smooth transition during this phase reduces the risk of dysbiosis, an imbalance in the gut flora associated with diarrhoea, reduced growth and increased susceptibility to infections.
What does the gut microbiome do for the health of the animal?
The gut microbiome fulfils several indispensable functions for the health of livestock. It supports digestion, strengthens the gut barrier, trains the immune system and protects against pathogens. A healthy and diverse microbiome is therefore one of the most important pillars of animal health and welfare.
The main functions are:
- Digestion and nutrient utilisation: Gut bacteria break down complex carbohydrates and fibres into short-chain fatty acids (SCFA), such as butyrate, acetate and propionate. These fatty acids are an energy source for intestinal cells and support gut integrity.
- Immune modulation: The microbiome stimulates the development and maturation of the immune system. Beneficial bacteria help the animal distinguish between harmful and harmless substances.
- Protection against pathogens: Through competition for nutrients and attachment sites, beneficial bacteria keep harmful micro-organisms in check. This mechanism is called competitive exclusion.
- Production of vitamins: Certain gut bacteria synthesise vitamins, including vitamin K and B vitamins, which the animal itself cannot produce or produces insufficiently.
- Strengthening the gut barrier: A healthy microbiome stimulates the expression of tight junction proteins that seal the intestinal wall and prevent the entry of harmful substances.
Which factors disrupt the gut microbiome in livestock?
The gut microbiome in livestock is sensitive to a wide range of internal and external factors. Stress, dietary changes, infections and the use of antibiotics are the most common causes of dysbiosis. When the balance is disrupted, diversity decreases and pathogenic bacteria can gain the upper hand.
The main disruptive factors at a glance:
- Heat stress: High ambient temperatures reduce blood flow to the gut and increase the permeability of the intestinal wall. This increases the risk of bacterial translocation and inflammation.
- Antibiotic use: Antibiotics kill not only pathogens, but also beneficial bacteria, leading to a disrupted microbiota and an increased risk of resistance development.
- Dietary changes: Abrupt transitions in the feed regime, such as weaning or changing the raw material composition, disrupt the microbiome balance.
- Infections and coccidiosis: Parasitic and bacterial infections damage the intestinal wall and directly disrupt the microbiota composition.
- Hygiene and housing conditions: A high bacterial load in the environment, contaminated drinking water or wet litter increase the risk of pathogenic colonisation.
- Nutrient deficiencies: A shortage of certain nutrients, such as choline or essential amino acids, undermines the integrity of the intestinal wall and the animal’s resilience.
How can nutrition positively influence the gut microbiome?
Nutrition is one of the most powerful tools for positively steering the gut microbiome in livestock. Certain nutrients and additives promote the growth of beneficial bacteria, strengthen the intestinal wall and inhibit the growth of pathogens. A well-considered nutritional strategy therefore directly contributes to a stable and healthy gut flora.
Prebiotics, such as fermentable fibres and specific sugars, serve as a nutritional source for beneficial bacteria such as Lactobacillus and Bifidobacterium. Probiotics add live micro-organisms to feed or drinking water and help improve the microbiota composition. Organic acids lower the pH in the gastrointestinal tract, which inhibits the growth of gram-negative pathogens such as E. coli and Salmonella.
Medium-chain fatty acids (MCFA), such as caprylic acid (C8), capric acid (C10) and lauric acid (C12), have a direct antimicrobial effect on harmful bacteria, while leaving beneficial species unaffected. Butyrate, a short-chain fatty acid, strengthens gut integrity by stimulating the expression of tight junction proteins and reducing intestinal inflammation. More information about Grovax and gut health shows how these ingredients are combined in practice.
Betaine also plays a role in gut health: it increases villus height and reduces crypt depth, leading to a larger absorption surface and better nutrient utilisation. As an osmolyte, betaine protects intestinal cells during heat stress and infections, and it promotes a healthy microbiome balance by supporting eubiosis.
What is the relationship between the gut microbiome and production performance?
A healthy gut microbiome is directly linked to better production performance in livestock. Animals with a stable, diverse gut flora dominated by beneficial bacteria grow faster, utilise feed more efficiently and are less susceptible to disease. The link between microbiome health and technical performance is well supported by science.
In broilers, better gut integrity leads to a higher feed conversion ratio (FCR) and higher breast muscle yield. When the intestinal wall is intact, nutrients are better absorbed and less energy is lost to inflammatory responses. In laying hens, a healthy microbiome translates into more stable egg production, better shell strength and longer laying persistence.
In pigs, the connections are similar: piglets with a well-developed gut microbiome after weaning grow better and have a lower risk of post-weaning diarrhoea. In ruminants, the rumen microbiome directly influences milk production and carcass quality, partly through the ratio of short-chain fatty acids and the efficiency of microbial protein synthesis.
In short: investing in a healthy gut microbiome is investing in the technical and economic performance of the business. More background on the relationship between betaine and animal performance offers further depth on this topic.
How Jodoco helps with a healthy gut microbiome in livestock
At Jodoco, we combine more than 25 years of experience with scientifically substantiated ingredients to actively support the gut microbiome of livestock. Our products are developed from the conviction that healthy animals form the foundation for sustainable and efficient food production.
Concretely, we offer the following solutions for a healthy gut microbiome:
- Jodobet: Natural betaine that strengthens the gut barrier through increased expression of tight junction proteins, increases villus height and promotes eubiosis.
- Grovax: A combination of organic acids, slow-release butyrate, MCFA and essential oils that improves gut health, inhibits pathogenic bacteria and fits within an antibiotic-free strategy.
- Jodoplume: A liquid combination of betaine, organic acids and copper for use via drinking water, ideal during heat stress or coccidiosis.
Our products are available for poultry, pigs and ruminants and are administered via feed and drinking water. They are free from GMOs, certified in accordance with EU legislation and developed in our own laboratories in collaboration with universities and research institutes. Discover our complete range of drinking water and feed additives or contact us directly for tailored advice.
Would you like to know which products best suit your farm situation? Contact our team and we will be happy to help you.


